World First Aid Day | An Early Screening Solution for Acute Myocardial Infarction (AMI)
Observed on the second Saturday of September each year, World First Aid Day promotes public awareness of lifesaving skills.
Common Emergency Scenarios
In our daily lives, we often encounter complex and unpredictable emergencies or injuries that require different first aid knowledge to handle and respond to. The following are several common emergency scenarios:
- Cardiac Arrest – Cardiac arrest is mostly a pathological condition that requires timely medical attention to identify the cause. In the event of a sudden occurrence, timely use of cardiopulmonary resuscitation (CPR) and an automated external defibrillator (AED) is crucial to improving the success rate of treatment and the likelihood of a good prognosis.
- Airway Obstruction – Mostly caused by hard objects blocking the respiratory tract; other conditions require timely medical attention to identify the cause. For hard object obstruction, the Heimlich maneuver, back blows, and self-abdominal thrusts are the main rescue methods.
- Drowning – After the victim is brought ashore, foreign objects in the mouth and nose should be cleared as soon as possible in a lateral position, and rescue breathing and chest compressions should be performed promptly.
- Electrical Shock – Ensure your own safety and immediately cut off the power source. If the patient is unconscious and not breathing, immediately perform cardiopulmonary resuscitation.
- Burns and Scalds – Quickly rinse the affected area with room-temperature water (15-25°C) continuously to cool it down. In cases of severe thirst, the patient may orally consume a small amount of light salt water or light salt tea.
Among the above emergency scenarios, cardiac arrest and airway obstruction are the most challenging, requiring rescuers to master certain first aid skills and response measures, and to promptly call emergency services (120) for follow-up rescue.
Beyond mastering first aid measures, acute myocardial infarction can also be prevented through examination. Early screening, early diagnosis, and early treatment can block the disease in its early stages, avoiding subsequent high-risk events.
Clinical Manifestations and Biomarkers of AMI
Acute myocardial infarction (AMI) is myocardial necrosis caused by acute and sustained ischemia and hypoxia of the coronary arteries. Typical symptoms of acute myocardial infarction include sudden severe pain lasting more than half an hour, often accompanied by restlessness, cold sweats, and a sense of fear. Atypical symptoms include sore throat, shoulder pain, toothache, stomachache, and pain in the back and jaw.
In China, the incidence and mortality rates of coronary heart disease, especially acute myocardial infarction, are rising year by year and showing a trend toward younger patients. The incidence of AMI decreases as the age cutoff value decreases. In daily life, patients should receive treatment within 3-6 hours of onset (no more than 12 hours) to allow the occluded coronary artery to reopen. The time from first medical contact to PCI should be controlled within 90 minutes. For hospitals that cannot perform emergency PCI, patients should be transferred as quickly as possible to hospitals with direct PCI capabilities.
Cardiac biomarkers are biochemical indicators that reflect heart disease and are helpful for early diagnosis, clinical stratification, and prognosis evaluation of myocardial injury, particularly acute myocardial infarction due to coronary heart disease. Currently, AMI biomarkers widely used in clinical practice include cardiac troponin (cTnI/cTnT), creatine kinase isoenzyme (CK-MB), myoglobin (Myo), D-dimer (D-Dimer), and N-terminal pro-brain natriuretic peptide / brain natriuretic peptide (NT-proBNP/BNP). Single or combined detection of different biomarkers is used to determine different stages of AMI development and reinfarction.
Common cardiac biomarkers include:
Virtue Diagnostics Cardiac Marker Testing Solution
Virtue Diagnostics, combining patient characteristics and testing needs, offers a rapid POCT testing solution: five cardiac markers (hs-cTnI, CK-MB, Myoglobin, NT-proBNP, D-Dimer) plus four inflammatory markers (CRP, SAA, PCT, IL-6), completing important screening indicators within 20 minutes.
The SuperFlex® single-test chemiluminescence platform is built around the two core features of "precision" and "flexibility," focusing on critical and emergency care, providing timely and reliable cardiovascular and inflammatory marker diagnostics for clinical departments, emergency and outpatient laboratories, and central laboratories.
Key Product Features
High Performance
High-sensitivity cardiac troponin detection reagent with a 99th percentile detection value as low as 30 ng/L (CV < 10%), and a detection rate of > 50% in apparently healthy populations.
Fast Turnaround
Myoglobin detection time is 6 minutes; CK-MB and hs-cTnI detection time is 12 minutes.
Flexible Samples
Supports serum, plasma, and whole blood sample types.
Comprehensive QC
Compatible with commercial quality control materials for reliable quality assurance.
Stable Operation
One calibration sustains operation for 28 days, with single-test reagents in independent packaging.
About Virtue Diagnostics
Founded in 2019, Virtue Diagnostics has assembled a team of management talents with many years of rich experience in the in vitro diagnostics industry and a global perspective, possessing strong R&D, operational, and commercialization capabilities. The company has established industrialization bases in China, Brazil, and Indonesia, and R&D centers in Singapore, China, and Brazil. Through cooperative R&D, investment, mergers and acquisitions, and other commercial means, Virtue Diagnostics is expanding its global market presence.
